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Explaining tdr5 years ago
Introduction | Size investing and tdr
Real data examples5 years ago
Panel a) | Panel b) | Proteomics Example | panel c) | Panel d) | hQTL Example | Load in data | Panel e) | Panel f) | Put all panels together for main fig! | Put all panels together for suppl fig.
hQTL analysis with IHW-Benjamini-Yekutieli5 years ago
Histogram plots | Apply IHW-BY and BY | Hypotheses shown in table | Set out to do the weight/threshold/lfdr plots | Start the plotting | Weights chromosome 1
Simulation Results6 years ago
Panels a,b | Data for panels a,b | Panel a) | Panel b) | Panels a, b) | Panels c, d) | Data for panels c,d) | Panel c) | Panel d) | Put panels c), d) together: | Panels e),f) | Load data for panels e),f) | Panel e) | Panel f) | Combine main panels for size investing | Combine everything into main text simulation figure | New main fig sim. figures without borders: | Supplementary panel b) | Combine supplementary effect size simulations | Supplementary Size Investing | Supplementary Panel c), FDR in size investing simulations | Supplementary Panel d), Power in size investing simulations | Combine supplemental size investing panels | Full supplementary simulations figure | New supplementary simulations figure
Grenander Estimator as applied to IHW (vs ECDF)6 years ago
IHW-Bonferroni simulations8 years ago
Null simulation | FWER control | Effect size simulation (t-test) | Power | Size investing simulation | Composite panel:
Stratified Histograms8 years ago
Old example | Examples for Figure 1 of paper | Figure 1 of paper
BH explanation / visualization8 years ago
B.Sc. thesis plot (low $\pi_0$) | Bioc presentation plot (higher $\pi_0$)
Real data examples: 1-fold weight function8 years ago
DESeq2 Bottomly | hQTL example
tdr and pvalue rejection regions8 years ago
Weights vs Independent Filtering8 years ago
Introduction to Independent Hypothesis Weighting with the IHW Package10 years ago
Introduction | An example: RNA-Seq differential expression | FDR control | Diagnostic plots | Estimated weights | Decision boundary | Raw versus adjusted p-values | FWER control with IHW | Other data types, and how to choose the covariate | Criteria for choosing a covariate | Examples | Why are the different covariate criteria necessary? | Diagnostic plots for the covariate | Scatter plots | Stratified p-value histograms | Further reading about appropriate covariates | Advanced usage: Working with incomplete p-value lists | References